diff --git a/pkgs/development/python-modules/mox/default.nix b/pkgs/development/python-modules/mox/default.nix
deleted file mode 100644
index 3513ac2b2cc8..000000000000
--- a/pkgs/development/python-modules/mox/default.nix
+++ /dev/null
@@ -1,41 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchFromGitHub
-, pytestCheckHook
-, pythonOlder
-, six
-}:
-
-buildPythonPackage rec {
-  pname = "mox";
-  version = "0.7.8";
-  format = "setuptools";
-
-  disabled = pythonOlder "3.7";
-
-  src = fetchFromGitHub {
-    owner = "ivancrneto";
-    repo = "pymox";
-    rev = "v${version}";
-    hash = "sha256-gODE9IGDk3WtO8iPOlp98fGp6Ih2laA3YlOHmq62m8Y=";
-  };
-
-  propagatedBuildInputs = [
-    six
-  ];
-
-  nativeCheckInputs = [
-    pytestCheckHook
-  ];
-
-  pythonImportsCheck = [
-    "mox"
-  ];
-
-  meta = with lib; {
-    description = "Mock object framework";
-    homepage = "https://github.com/ivancrneto/pymox";
-    license = licenses.asl20;
-    maintainers = with maintainers; [ ];
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index b2e8033b97e4..04749a61430c 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -130,6 +130,7 @@ mapAliases ({
   mailman-web = throw "Please use pkgs.mailman-web"; # added 2022-04-29
   mistune_0_8 = throw "mistune_0_8 was removed because it was outdated and insecure"; # added 2022-08-12
   mistune_2_0 = mistune; # added 2022-08-12
+  mox = throw "mox was removed because it is unmaintained"; # added 2023-02-21
   mutmut = throw "mutmut has been promoted to a top-level attribute"; # added 2022-10-02
   net2grid = gridnet; # add 2022-04-22
   nose-cover3 = throw "nose-cover3 has been removed, it was using setuptools 2to3 translation feature, which has been removed in setuptools 58"; # added 2022-02-16
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 28812e165401..422e6cbb533d 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -6074,8 +6074,6 @@ self: super: with self; {
 
   mox3 = callPackage ../development/python-modules/mox3 { };
 
-  mox = callPackage ../development/python-modules/mox { };
-
   mpd2 = callPackage ../development/python-modules/mpd2 { };
 
   mpi4py = callPackage ../development/python-modules/mpi4py { };