diff --git a/pkgs/applications/audio/audacity/default.nix b/pkgs/applications/audio/audacity/default.nix
index 653d5555eb14..953e9887f5a6 100644
--- a/pkgs/applications/audio/audacity/default.nix
+++ b/pkgs/applications/audio/audacity/default.nix
@@ -167,6 +167,9 @@ in stdenv.mkDerivation rec {
     "-DDISABLE_DYNAMIC_LOADING_FFMPEG=ON"
     "-Daudacity_conan_enabled=Off"
     "-Daudacity_use_ffmpeg=loaded"
+
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
   ];
 
   doCheck = false; # Test fails
diff --git a/pkgs/applications/audio/tenacity/default.nix b/pkgs/applications/audio/tenacity/default.nix
index fbf13c1748ff..89051e70b519 100644
--- a/pkgs/applications/audio/tenacity/default.nix
+++ b/pkgs/applications/audio/tenacity/default.nix
@@ -138,6 +138,11 @@ stdenv.mkDerivation rec {
     util-linux
   ];
 
+  cmakeFlags = [
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
+  ];
+
   meta = with lib; {
     description = "Sound editor with graphical UI";
     homepage = "https://tenacityaudio.org/";
diff --git a/pkgs/applications/networking/instant-messengers/linphone/default.nix b/pkgs/applications/networking/instant-messengers/linphone/default.nix
index 306a53f0a3c0..71299566dd87 100644
--- a/pkgs/applications/networking/instant-messengers/linphone/default.nix
+++ b/pkgs/applications/networking/instant-messengers/linphone/default.nix
@@ -83,6 +83,9 @@ mkDerivation rec {
   cmakeFlags = [
     "-DMINIZIP_INCLUDE_DIRS=${minizip2}/include"
     "-DMINIZIP_LIBRARIES=minizip"
+
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
   ];
 
   # The default install phase fails because the paths are somehow messed up in
diff --git a/pkgs/applications/science/electronics/kicad/base.nix b/pkgs/applications/science/electronics/kicad/base.nix
index 0fbd824008a5..aa5d9a7ade19 100644
--- a/pkgs/applications/science/electronics/kicad/base.nix
+++ b/pkgs/applications/science/electronics/kicad/base.nix
@@ -75,7 +75,11 @@ stdenv.mkDerivation rec {
 
   makeFlags = optionals (debug) [ "CFLAGS+=-Og" "CFLAGS+=-ggdb" ];
 
-  cmakeFlags = optionals (withScripting) [
+  cmakeFlags = [
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
+  ]
+  ++ optionals (withScripting) [
     "-DKICAD_SCRIPTING_WXPYTHON=ON"
   ]
   ++ optionals (!withScripting) [
diff --git a/pkgs/development/libraries/libqtav/default.nix b/pkgs/development/libraries/libqtav/default.nix
index 090291a120f7..c2d91b1d5b73 100644
--- a/pkgs/development/libraries/libqtav/default.nix
+++ b/pkgs/development/libraries/libqtav/default.nix
@@ -52,6 +52,11 @@ mkDerivation rec {
   # the other libraries as `libGL` is part of our `buildInputs`.
   NIX_CFLAGS_LINK = "-Wl,-rpath,${libGL}/lib";
 
+  cmakeFlags = [
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
+  ];
+
   preFixup = ''
     mkdir -p "$out/bin"
     cp -a "./bin/"* "$out/bin"
diff --git a/pkgs/development/libraries/mlt/qt-5.nix b/pkgs/development/libraries/mlt/qt-5.nix
index 11a63a3cd5ce..9cf5da3e395b 100644
--- a/pkgs/development/libraries/mlt/qt-5.nix
+++ b/pkgs/development/libraries/mlt/qt-5.nix
@@ -60,6 +60,11 @@ mkDerivation rec {
 
   outputs = [ "out" "dev" ];
 
+  cmakeFlags = [
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
+  ];
+
   qtWrapperArgs = [
     "--prefix FREI0R_PATH : ${frei0r}/lib/frei0r-1"
     "--prefix LADSPA_PATH : ${ladspaPlugins}/lib/ladspa"
diff --git a/pkgs/games/mudlet/default.nix b/pkgs/games/mudlet/default.nix
index f4ca916aa499..b2696d727887 100644
--- a/pkgs/games/mudlet/default.nix
+++ b/pkgs/games/mudlet/default.nix
@@ -62,6 +62,11 @@ stdenv.mkDerivation rec {
     yajl
   ];
 
+  cmakeFlags = [
+    # RPATH of binary /nix/store/.../bin/... contains a forbidden reference to /build/
+    "-DCMAKE_SKIP_BUILD_RPATH=ON"
+  ];
+
   WITH_FONTS = "NO";
   WITH_UPDATER = "NO";