diff --git a/pkgs/development/python-modules/aioquic/default.nix b/pkgs/development/python-modules/aioquic/default.nix
index 9ea35ea2d668..7b6c8890f887 100644
--- a/pkgs/development/python-modules/aioquic/default.nix
+++ b/pkgs/development/python-modules/aioquic/default.nix
@@ -1,5 +1,6 @@
 { lib
 , fetchPypi
+, fetchpatch
 , buildPythonPackage
 , openssl
 , pylsqpack
@@ -17,6 +18,19 @@ buildPythonPackage rec {
     sha256 = "sha256-7ENqqs6Ze4RrAeUgDtv34+VrkYJqFE77l0j9jd0zK74=";
   };
 
+  patches = [
+    # This patch is here because it's required by the next patch.
+    (fetchpatch {
+      url = "https://github.com/aiortc/aioquic/commit/3930580b50831a034d21ee4689362188b21a4d6a.patch";
+      hash = "sha256-XjhyajDawN/G1nPtkMbNe66iJCo76UpdA7PqwtxO5ag=";
+    })
+    # https://github.com/aiortc/aioquic/pull/349, fixes test failure due pyopenssl==22
+    (assert lib.versions.major pyopenssl.version == "22"; fetchpatch {
+      url = "https://github.com/aiortc/aioquic/commit/c3b72be85868d67ee32d49ab9bd98a4357cbcde9.patch";
+      hash = "sha256-AjW+U9DpNXgA5yqKkWnx0OYpY2sZR9KIdQ3pSzxU+uY=";
+    })
+  ];
+
   propagatedBuildInputs = [
     certifi
     pylsqpack