diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 142095bb5366..00f1e031b543 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -11348,12 +11348,12 @@ in modules // {
   };
 
   ipython = buildPythonPackage rec {
-    version = "4.1.2";
+    version = "5.0.0";
     name = "ipython-${version}";
 
     src = pkgs.fetchurl {
       url = "mirror://pypi/i/ipython/${name}.tar.gz";
-      sha256 = "14hnf3m087z39ndn5irj1ficc6l197bmdj6fpvz8bwi7la99cbq5";
+      sha256 = "7ec0737169c74056c7fc8298246db5478a2d6c90cfd19c3253222112357545df";
     };
 
     prePatch = stdenv.lib.optionalString stdenv.isDarwin ''
@@ -11363,8 +11363,8 @@ in modules // {
     buildInputs = with self; [ nose pkgs.glibcLocales pygments ] ++ optionals isPy27 [mock];
 
     propagatedBuildInputs = with self;
-      [decorator pickleshare simplegeneric traitlets readline requests2 pexpect sqlite3]
-      ++ optionals stdenv.isDarwin [appnope gnureadline];
+      [decorator pickleshare prompt_toolkit simplegeneric traitlets requests2 pexpect sqlite3]
+      ++ optionals stdenv.isDarwin [appnope];
 
     LC_ALL="en_US.UTF-8";