diff --git a/pkgs/development/python-modules/symengine/default.nix b/pkgs/development/python-modules/symengine/default.nix
new file mode 100644
index 000000000000..7e10c02460e8
--- /dev/null
+++ b/pkgs/development/python-modules/symengine/default.nix
@@ -0,0 +1,43 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+, cython
+, cmake
+, symengine
+, nose
+}:
+
+buildPythonPackage rec {
+  pname = "symengine";
+  version = "0.3.0";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "e86d13aadc9f765f2c5462da32950edd36d1a0a52dbfc96e766be3689957c04d";
+  };
+
+  postConfigure = ''
+    substituteInPlace setup.py \
+      --replace "\"cmake\"" "\"${cmake}/bin/cmake\""
+
+    substituteInPlace cmake/FindCython.cmake \
+      --replace "SET(CYTHON_BIN cython" "SET(CYTHON_BIN ${cython}/bin/cython"
+  '';
+
+  buildInputs = [ cython cmake ];
+
+  setupPyBuildFlags = [ "--symengine-dir=${symengine}/" ];
+
+  # tests fail due to trying to import local "symengine" directory
+  doCheck = false;
+  checkPhase = ''
+    nosetests symengine/tests -v
+  '';
+
+  meta = with lib; {
+    description = "Python library providing wrappers to SymEngine";
+    homepage = https://github.com/symengine/symengine.py;
+    license = licenses.mit;
+    maintainers = [ maintainers.costrouc ];
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index a7e223e160c1..c01b86d4f201 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -5937,6 +5937,8 @@ in
 
   svtplay-dl = callPackage ../tools/misc/svtplay-dl { };
 
+  symengine = callPackage ../development/libraries/symengine { };
+
   sysbench = callPackage ../development/tools/misc/sysbench {};
 
   system-config-printer = callPackage ../tools/misc/system-config-printer {