diff --git a/pkgs/development/libraries/glibc/default.nix b/pkgs/development/libraries/glibc/default.nix
index 728b97d2f5f4..5f581d7493e3 100644
--- a/pkgs/development/libraries/glibc/default.nix
+++ b/pkgs/development/libraries/glibc/default.nix
@@ -38,6 +38,9 @@ callPackage ./common.nix { inherit stdenv; } {
 
       # Apparently --bindir is not respected.
       makeFlagsArray+=("bindir=$bin/bin" "sbindir=$bin/sbin" "rootsbindir=$bin/sbin")
+    '' + lib.optionalString stdenv.buildPlatform.isDarwin ''
+      # ld-wrapper will otherwise attempt to inject CoreFoundation into ld-linux's RUNPATH
+      export NIX_COREFOUNDATION_RPATH=
     '';
 
     # The pie, stackprotector and fortify hardening flags are autodetected by