diff --git a/pkgs/development/libraries/ffmpeg-full/default.nix b/pkgs/development/libraries/ffmpeg-full/default.nix
index db606cc02d63..e3517a46e44c 100644
--- a/pkgs/development/libraries/ffmpeg-full/default.nix
+++ b/pkgs/development/libraries/ffmpeg-full/default.nix
@@ -97,7 +97,7 @@
 , libXv ? null # Xlib support
 , libXext ? null # Xlib support
 , lzma ? null # xz-utils
-, nvenc ? true, nv-codec-headers ? null # NVIDIA NVENC support
+, nvenc ? !stdenv.isDarwin, nv-codec-headers ? null # NVIDIA NVENC support
 , openal ? null # OpenAL 1.1 capture support
 #, opencl ? null # OpenCL code
 , opencore-amr ? null # AMR-NB de/encoder & AMR-WB decoder
@@ -175,7 +175,7 @@
  */
 
 let
-  inherit (stdenv) isCygwin isFreeBSD isLinux;
+  inherit (stdenv) isCygwin isDarwin isFreeBSD isLinux;
   inherit (stdenv.lib) optional optionals optionalString enableFeature;
 in
 
@@ -189,6 +189,10 @@ assert nonfreeLicensing -> gplLicensing && version3Licensing;
  */
 assert networkBuild -> gnutls != null || opensslExtlib;
 assert pixelutilsBuild -> avutilLibrary;
+/*
+ *  Platform dependencies
+ */
+assert isDarwin -> !nvenc;
 /*
  *  Program dependencies
  */