diff --git a/pkgs/development/python-modules/mask-rcnn/default.nix b/pkgs/development/python-modules/mask-rcnn/default.nix
deleted file mode 100644
index 471b1fa61d42..000000000000
--- a/pkgs/development/python-modules/mask-rcnn/default.nix
+++ /dev/null
@@ -1,68 +0,0 @@
-{ buildPythonPackage
-, cython
-, fetchFromGitHub
-, fetchpatch
-, h5py
-, imgaug
-, ipython
-, keras
-, lib
-, matplotlib
-, numpy
-, opencv3
-, pillow
-, scikit-image
-, scipy
-, tensorflow
-}:
-
-buildPythonPackage rec {
-  pname = "mask-rcnn";
-  version = "2.1";
-
-  src = fetchFromGitHub {
-    owner = "matterport";
-    repo = "Mask_RCNN";
-    rev = "3deaec5d902d16e1daf56b62d5971d428dc920bc";
-    sha256 = "13s3q9yh2q9m9vyksd269mww3bni4q2w7q5l419q70ca075qp8zp";
-  };
-
-  patches = [
-    # Fix for TF2:
-    # https://github.com/matterport/Mask_RCNN/issues/2734
-    (fetchpatch {
-      url = "https://github.com/BupyeongHealer/Mask_RCNN_tf_2.x/commit/7957839fe2b248f2f22c7e991ead12068ddc6cfc.diff";
-      excludes = [ "mrcnn/model.py" ];
-      hash = "sha256-70BGrx6X1uJDA2025f0YTlreT2uB3n35yIzuhf+ypVc=";
-    })
-  ];
-
-  # Fix for recent Keras
-  postPatch = ''
-    substituteInPlace mrcnn/model.py \
-      --replace "KE." "KL."
-  '';
-
-  nativeBuildInputs = [ cython ];
-
-  propagatedBuildInputs = [
-    h5py
-    imgaug
-    ipython
-    keras
-    matplotlib
-    numpy
-    opencv3
-    pillow
-    scikit-image
-    scipy
-    tensorflow
-  ];
-
-  meta = with lib; {
-    description = "Mask R-CNN for object detection and instance segmentation on Keras and TensorFlow";
-    homepage = "https://github.com/matterport/Mask_RCNN";
-    license = licenses.mit;
-    maintainers = with maintainers; [ rakesh4g ];
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 0f4cc1b4072e..e4e0e8ce968b 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -172,6 +172,7 @@ mapAliases ({
   Mako = mako; # added 2023-02-19
   Markups = markups; # added 2022-02-14
   markdownsuperscript = throw "markdownsuperscript is unmaintained, use pymdown-extensions"; # added 2023-06-10
+  mask-rcnn = throw "mask-rcnn has been removed as it is unmaintained and its dependency imgaug no longer builds"; # added 2023-07-10
   MDP = mdp; # added 2023-02-19
   MechanicalSoup = mechanicalsoup; # added 2021-06-01
   memcached = python-memcached; # added 2022-05-06
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index c38c49c9ada7..6e2e7621339e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -6179,8 +6179,6 @@ self: super: with self; {
 
   mashumaro = callPackage ../development/python-modules/mashumaro { };
 
-  mask-rcnn = callPackage ../development/python-modules/mask-rcnn { };
-
   masky = callPackage ../development/python-modules/masky { };
 
   mastodon-py = callPackage ../development/python-modules/mastodon-py { };