diff --git a/pkgs/development/python-modules/angr/default.nix b/pkgs/development/python-modules/angr/default.nix
new file mode 100644
index 000000000000..ba0b3b68be26
--- /dev/null
+++ b/pkgs/development/python-modules/angr/default.nix
@@ -0,0 +1,93 @@
+{ lib
+, ailment
+, archinfo
+, buildPythonPackage
+, cachetools
+, capstone
+, cffi
+, claripy
+, cle
+, cppheaderparser
+, dpkt
+, fetchFromGitHub
+, GitPython
+, itanium_demangler
+, mulpyplexer
+, networkx
+, progressbar2
+, protobuf
+, psutil
+, pycparser
+, pkgs
+, pythonOlder
+, pyvex
+, sqlalchemy
+, rpyc
+, sortedcontainers
+, unicorn
+}:
+
+let
+  # Only the pinned release in setup.py works properly
+  unicorn' = unicorn.overridePythonAttrs (old: rec {
+      pname = "unicorn";
+      version = "1.0.2-rc4";
+      src =  fetchFromGitHub {
+        owner = "unicorn-engine";
+        repo = pname;
+        rev = version;
+        sha256 = "17nyccgk7hpc4hab24yn57f1xnmr7kq4px98zbp2bkwcrxny8gwy";
+    };
+  });
+in
+
+buildPythonPackage rec {
+  pname = "angr";
+  version = "9.0.6281";
+  disabled = pythonOlder "3.6";
+
+  src = fetchFromGitHub {
+    owner = pname;
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "10i4qdk8f342gzxiwy0pjdc35lc4q5ab7l5q420ca61cgdvxkk4r";
+  };
+
+  propagatedBuildInputs = [
+    ailment
+    archinfo
+    cachetools
+    capstone
+    cffi
+    claripy
+    cle
+    cppheaderparser
+    dpkt
+    GitPython
+    itanium_demangler
+    mulpyplexer
+    networkx
+    progressbar2
+    protobuf
+    psutil
+    sqlalchemy
+    pycparser
+    pyvex
+    sqlalchemy
+    rpyc
+    sortedcontainers
+    unicorn'
+  ];
+
+  # Tests have additional requirements, e.g., pypcode and angr binaries
+  # cle is executing the tests with the angr binaries
+  doCheck = false;
+  pythonImportsCheck = [ "angr" ];
+
+  meta = with lib; {
+    description = "Powerful and user-friendly binary analysis platform";
+    homepage = "https://angr.io/";
+    license = with licenses; [ bsd2 ];
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 45622144e851..2f461f089422 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -378,6 +378,8 @@ in {
 
   androguard = callPackage ../development/python-modules/androguard { };
 
+  angr = callPackage ../development/python-modules/angr { };
+
   aniso8601 = callPackage ../development/python-modules/aniso8601 { };
 
   annexremote = callPackage ../development/python-modules/annexremote { };
@@ -1356,6 +1358,8 @@ in {
 
   cld2-cffi = callPackage ../development/python-modules/cld2-cffi { };
 
+  cle = callPackage ../development/python-modules/cle { };
+
   cleo = callPackage ../development/python-modules/cleo { };
 
   clf = callPackage ../development/python-modules/clf { };