diff --git a/pkgs/applications/emulators/punes/default.nix b/pkgs/applications/emulators/punes/default.nix
index b68b70c0ac44..529dce536430 100644
--- a/pkgs/applications/emulators/punes/default.nix
+++ b/pkgs/applications/emulators/punes/default.nix
@@ -1,13 +1,8 @@
-{ mkDerivation
-, stdenv
+{ stdenv
 , lib
 , fetchFromGitHub
 , fetchpatch
-, nix-update-script
-, qtbase
-, qtsvg
-, qttools
-, autoreconfHook
+, gitUpdater
 , cmake
 , pkg-config
 , ffmpeg
@@ -16,41 +11,63 @@
 , libX11
 , libXrandr
 , sndio
+, qtbase
+, qtsvg
+, qttools
+, wrapQtAppsHook
 }:
 
-mkDerivation rec {
+stdenv.mkDerivation rec {
   pname = "punes";
-  version = "0.109";
+  version = "0.110";
 
   src = fetchFromGitHub {
     owner = "punesemu";
     repo = "puNES";
     rev = "v${version}";
-    sha256 = "sha256-6aRtR/d8nhzmpN9QKSZ62jye7qjfO+FpRMCXkX4Yubk=";
+    sha256 = "sha256-+hL168r40aYUjyLbWFXWk9G2srrrG1TH1gLYMliHftU=";
   };
 
-  postPatch = ''
-    substituteInPlace configure.ac \
-      --replace '`$PKG_CONFIG --variable=host_bins Qt5Core`/lrelease' '${qttools.dev}/bin/lrelease'
-  '';
-
-  nativeBuildInputs = [ autoreconfHook cmake pkg-config qttools ];
-
-  buildInputs = [ ffmpeg qtbase qtsvg libGLU ]
-    ++ lib.optionals stdenv.hostPlatform.isLinux [ alsa-lib libX11 libXrandr ]
-    ++ lib.optionals stdenv.hostPlatform.isBSD [ sndio ];
-
-  dontUseCmakeConfigure = true;
-
-  enableParallelBuilding = true;
-
-  configureFlags = [
-    "--prefix=${placeholder "out"}"
-    "--without-opengl-nvidia-cg"
-    "--with-ffmpeg"
+  patches = [
+    # Fixes compilation on aarch64
+    # Remove when version > 0.110
+    (fetchpatch {
+      url = "https://github.com/punesemu/puNES/commit/90dd5bc90412bbd199c2716f67a24aa88b24d80f.patch";
+      hash = "sha256-/KNpTds4qjwyaTUebWWPlVXfuxVh6M4zOInxUfYztJg=";
+    })
   ];
 
-  passthru.updateScript = nix-update-script { };
+  nativeBuildInputs = [
+    cmake
+    pkg-config
+    qttools
+    wrapQtAppsHook
+  ];
+
+  buildInputs = [
+    ffmpeg
+    libGLU
+    qtbase
+    qtsvg
+  ] ++ lib.optionals stdenv.hostPlatform.isLinux [
+    alsa-lib
+    libX11
+    libXrandr
+  ] ++ lib.optionals stdenv.hostPlatform.isBSD [
+    sndio
+  ];
+
+  cmakeFlags = [
+    "-DENABLE_GIT_INFO=OFF"
+    "-DENABLE_RELEASE=ON"
+    "-DENABLE_FFMPEG=ON"
+    "-DENABLE_OPENGL=ON"
+    "-DENABLE_QT6_LIBS=${if lib.versionAtLeast qtbase.version "6.0" then "ON" else "OFF"}"
+  ];
+
+  passthru.updateScript = gitUpdater {
+    rev-prefix = "v";
+  };
 
   meta = with lib; {
     description = "Qt-based Nintendo Entertainment System emulator and NSF/NSFe Music Player";
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 05606f94a7cf..763a6e0e62dd 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -2189,6 +2189,8 @@ with pkgs;
 
   punes = libsForQt5.callPackage ../applications/emulators/punes { };
 
+  punes-qt6 = qt6Packages.callPackage ../applications/emulators/punes { };
+
   py65 = python3Packages.callPackage ../applications/emulators/py65 { };
 
   resim = callPackage ../applications/emulators/resim {};