diff --git a/pkgs/tools/misc/cyclonedx-python/default.nix b/pkgs/tools/misc/cyclonedx-python/default.nix
new file mode 100644
index 000000000000..97dfd8310da5
--- /dev/null
+++ b/pkgs/tools/misc/cyclonedx-python/default.nix
@@ -0,0 +1,47 @@
+{ lib
+, python3
+, fetchFromGitHub
+}:
+python3.pkgs.buildPythonApplication rec {
+  pname = "cyclonedx-python";
+  version = "0.4.3";
+
+  src = fetchFromGitHub {
+    owner = "CycloneDX";
+    repo = "cyclonedx-python";
+    rev = "v${version}";
+    sha256 = "BvG4aWBMsllW2L4lLsiRFUCPjgoDpHxN49fsUFdg7tQ=";
+  };
+
+  # They pin versions for exact version numbers because "A bill-of-material such
+  # as CycloneDX expects exact version numbers" -- but that's unnecessary with
+  # Nix.
+  preBuild = ''
+    sed "s@==.*'@'@" -i setup.py
+  '';
+
+  propagatedBuildInputs = with python3.pkgs; [
+    packageurl-python
+    requests
+    xmlschema
+    setuptools
+    requirements-parser
+    packaging
+    chardet
+    jsonschema
+  ];
+
+  # the tests want access to the cyclonedx binary
+  doCheck = false;
+
+  pythonImportsCheck = [
+    "cyclonedx"
+  ];
+
+  meta = with lib; {
+    description = "Creates CycloneDX Software Bill of Materials (SBOM) from Python projects";
+    homepage = "https://github.com/CycloneDX/cyclonedx-python";
+    license = licenses.asl20;
+    maintainers = teams.determinatesystems.members;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index e90dcf0345fe..f70a05f3ed15 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -1300,6 +1300,8 @@ in
 
   cyclone-scheme = callPackage ../development/interpreters/cyclone { };
 
+  cyclonedx-python = callPackage ../tools/misc/cyclonedx-python { };
+
   deltachat-electron = callPackage
     ../applications/networking/instant-messengers/deltachat-electron { };