diff --git a/pkgs/applications/science/math/R/default.nix b/pkgs/applications/science/math/R/default.nix
index 0a9a976f18a3..815d108ce412 100644
--- a/pkgs/applications/science/math/R/default.nix
+++ b/pkgs/applications/science/math/R/default.nix
@@ -33,11 +33,15 @@ stdenv.mkDerivation rec {
     ./no-usr-local-search-paths.patch
   ];
 
+  # Test of the examples for package 'tcltk' fails in Darwin sandbox. See:
+  # https://github.com/NixOS/nixpkgs/issues/146131
   prePatch = lib.optionalString stdenv.isDarwin ''
     substituteInPlace configure \
       --replace "-install_name libRblas.dylib" "-install_name $out/lib/R/lib/libRblas.dylib" \
       --replace "-install_name libRlapack.dylib" "-install_name $out/lib/R/lib/libRlapack.dylib" \
       --replace "-install_name libR.dylib" "-install_name $out/lib/R/lib/libR.dylib"
+    substituteInPlace tests/Examples/Makefile.in \
+      --replace "test-Examples: test-Examples-Base" "test-Examples:" # do not test the examples
   '';
 
   dontDisableStatic = static;