diff --git a/pkgs/development/tools/misc/binutils/default.nix b/pkgs/development/tools/misc/binutils/default.nix
index 8d759457fa11..ff89f1ad493a 100644
--- a/pkgs/development/tools/misc/binutils/default.nix
+++ b/pkgs/development/tools/misc/binutils/default.nix
@@ -13,6 +13,7 @@ in
 , flex
 , texinfo
 , perl
+, substitute
 }:
 
 # configure silently disables ld.gold if it's unsupported,
@@ -95,7 +96,13 @@ stdenv.mkDerivation {
        # this comment for more information:
        # https://gitlab.haskell.org/ghc/ghc/issues/4210#note_78333
        lib.optional (stdenv.targetPlatform.isAarch32 && stdenv.hostPlatform.system != stdenv.targetPlatform.system) ./R_ARM_COPY.patch
-    ++ lib.optional stdenv.targetPlatform.isWindows ./windres-locate-gcc.patch;
+    ++ lib.optional stdenv.targetPlatform.isWindows ./windres-locate-gcc.patch
+    ++ lib.optional stdenv.targetPlatform.isMips64n64
+       # this patch is from debian:
+       # https://sources.debian.org/data/main/b/binutils/2.38-3/debian/patches/mips64-default-n64.diff
+       (if stdenv.targetPlatform.isMusl
+        then substitute { src = ./mips64-default-n64.patch; replacements = [ "--replace" "gnuabi64" "muslabi64" ]; }
+        else ./mips64-default-n64.patch);
 
   outputs = [ "out" "info" "man" ];
 
diff --git a/pkgs/development/tools/misc/binutils/mips64-default-n64.patch b/pkgs/development/tools/misc/binutils/mips64-default-n64.patch
new file mode 100644
index 000000000000..00581279f85e
--- /dev/null
+++ b/pkgs/development/tools/misc/binutils/mips64-default-n64.patch
@@ -0,0 +1,82 @@
+--- a/bfd/config.bfd
++++ b/bfd/config.bfd
+@@ -927,11 +927,21 @@ case "${targ}" in
+     targ_defvec=mips_elf32_be_vec
+     targ_selvecs="mips_elf32_le_vec mips_elf64_be_vec mips_elf64_le_vec mips_ecoff_be_vec mips_ecoff_le_vec"
+     ;;
+-  mips64*el-*-linux*)
++  mips*64*el-*-linux*-gnuabi64)
++    targ_defvec=mips_elf64_trad_le_vec
++    targ_selvecs="mips_elf32_ntrad_be_vec mips_elf32_ntrad_le_vec mips_elf32_trad_be_vec mips_elf32_trad_le_vec mips_elf64_trad_be_vec"
++    want64=true
++    ;;
++  mips*64*-*-linux*-gnuabi64)
++    targ_defvec=mips_elf64_trad_be_vec
++    targ_selvecs="mips_elf32_ntrad_be_vec mips_elf32_ntrad_le_vec mips_elf32_trad_be_vec mips_elf32_trad_le_vec mips_elf64_trad_le_vec"
++    want64=true
++    ;;
++  mips*64*el-*-linux*)
+     targ_defvec=mips_elf32_ntrad_le_vec
+     targ_selvecs="mips_elf32_ntrad_be_vec mips_elf32_trad_le_vec mips_elf32_trad_be_vec mips_elf64_trad_le_vec mips_elf64_trad_be_vec"
+     ;;
+-  mips64*-*-linux*)
++  mips*64*-*-linux*)
+     targ_defvec=mips_elf32_ntrad_be_vec
+     targ_selvecs="mips_elf32_ntrad_le_vec mips_elf32_trad_be_vec mips_elf32_trad_le_vec mips_elf64_trad_be_vec mips_elf64_trad_le_vec"
+     ;;
+--- a/binutils/testsuite/binutils-all/mips/mips-note-2-n32.d
++++ b/binutils/testsuite/binutils-all/mips/mips-note-2-n32.d
+@@ -1,4 +1,5 @@
+ #PROG: objcopy
++#as: -n32
+ #readelf: --notes --wide
+ #objcopy: --merge-notes
+ #name: MIPS merge notes section (n32)
+--- a/gas/configure
++++ b/gas/configure
+@@ -12167,6 +12167,9 @@ _ACEOF
+ 	esac
+ 	# Decide which ABI to target by default.
+ 	case ${target} in
++	  mips*64*-linux-gnuabi64)
++	    mips_default_abi=N64_ABI
++	    ;;
+ 	  mips64*-linux* | mips-sgi-irix6* | mips64*-freebsd* \
+ 	  | mips64*-kfreebsd*-gnu | mips64*-ps2-elf*)
+ 	    mips_default_abi=N32_ABI
+--- a/gas/configure.ac
++++ b/gas/configure.ac
+@@ -384,6 +384,9 @@ changequote([,])dnl
+ 	esac
+ 	# Decide which ABI to target by default.
+ 	case ${target} in
++	  mips*64*-linux-gnuabi64)
++	    mips_default_abi=N64_ABI
++	    ;;
+ 	  mips64*-linux* | mips-sgi-irix6* | mips64*-freebsd* \
+ 	  | mips64*-kfreebsd*-gnu | mips64*-ps2-elf*)
+ 	    mips_default_abi=N32_ABI
+--- a/ld/configure.tgt
++++ b/ld/configure.tgt
+@@ -543,11 +543,19 @@ mips*-*-vxworks*)	targ_emul=elf32ebmipvx
+ 			;;
+ mips*-*-windiss)	targ_emul=elf32mipswindiss
+ 			;;
+-mips64*el-*-linux-*)	targ_emul=elf32ltsmipn32
++mips*64*el-*-linux-gnuabi64)	targ_emul=elf64ltsmip
++			targ_extra_emuls="elf32btsmipn32 elf32ltsmipn32 elf32ltsmip elf32btsmip elf64btsmip"
++			targ_extra_libpath=$targ_extra_emuls
++			;;
++mips*64*el-*-linux-*)	targ_emul=elf32ltsmipn32
+ 			targ_extra_emuls="elf32btsmipn32 elf32ltsmip elf32btsmip elf64ltsmip elf64btsmip"
+ 			targ_extra_libpath=$targ_extra_emuls
+ 			;;
+-mips64*-*-linux-*)	targ_emul=elf32btsmipn32
++mips*64*-*-linux-gnuabi64)	targ_emul=elf64btsmip
++			targ_extra_emuls="elf32btsmipn32 elf32ltsmipn32 elf32btsmip elf32ltsmip elf64ltsmip"
++			targ_extra_libpath=$targ_extra_emuls
++			;;
++mips*64*-*-linux-*)	targ_emul=elf32btsmipn32
+ 			targ_extra_emuls="elf32ltsmipn32 elf32btsmip elf32ltsmip elf64btsmip elf64ltsmip"
+ 			targ_extra_libpath=$targ_extra_emuls
+ 			;;