diff --git a/pkgs/development/libraries/quarto/default.nix b/pkgs/development/libraries/quarto/default.nix
index 47cfae648294..c9223aef6550 100644
--- a/pkgs/development/libraries/quarto/default.nix
+++ b/pkgs/development/libraries/quarto/default.nix
@@ -1,6 +1,7 @@
 { stdenv
 , lib
 , pandoc
+, typst
 , esbuild
 , deno
 , fetchurl
@@ -18,35 +19,31 @@
 
 stdenv.mkDerivation (final: {
   pname = "quarto";
-  version = "1.3.450";
+  version = "1.4.550";
   src = fetchurl {
     url = "https://github.com/quarto-dev/quarto-cli/releases/download/v${final.version}/quarto-${final.version}-linux-amd64.tar.gz";
-    sha256 = "sha256-bcj7SzEGfQxsw9P8WkcLrKurPupzwpgIGtxoE3KVwAU=";
+    sha256 = "sha256-cWHd7ZWGBdRTaSHYVa8LuTDA5gefJ5baOGERS2g6Vvg=";
   };
 
   nativeBuildInputs = [
     makeWrapper
   ];
 
-  patches = [
-    ./fix-deno-path.patch
-  ];
-
   postPatch = ''
     # Compat for Deno >=1.26
     substituteInPlace bin/quarto.js \
-      --replace 'Deno.setRaw(stdin.rid, ' 'Deno.stdin.setRaw(' \
-      --replace 'Deno.setRaw(Deno.stdin.rid, ' 'Deno.stdin.setRaw('
+      --replace-fail ']))?.trim();' ']))?.trim().split(" ")[0];'
   '';
 
   dontStrip = true;
 
   preFixup = ''
     wrapProgram $out/bin/quarto \
-      --prefix PATH : ${lib.makeBinPath [ deno ]} \
-      --prefix QUARTO_PANDOC : ${pandoc}/bin/pandoc \
-      --prefix QUARTO_ESBUILD : ${esbuild}/bin/esbuild \
-      --prefix QUARTO_DART_SASS : ${dart-sass}/bin/dart-sass \
+      --prefix QUARTO_DENO : ${lib.getExe deno} \
+      --prefix QUARTO_PANDOC : ${lib.getExe pandoc} \
+      --prefix QUARTO_ESBUILD : ${lib.getExe esbuild} \
+      --prefix QUARTO_DART_SASS : ${lib.getExe dart-sass} \
+      --prefix QUARTO_TYPST : ${lib.getExe typst} \
       ${lib.optionalString (rWrapper != null) "--prefix QUARTO_R : ${rWrapper.override { packages = [ rPackages.rmarkdown ] ++ extraRPackages; }}/bin/R"} \
       ${lib.optionalString (python3 != null) "--prefix QUARTO_PYTHON : ${python3.withPackages (ps: with ps; [ jupyter ipython ] ++ (extraPythonPackages ps))}/bin/python3"}
   '';
diff --git a/pkgs/development/libraries/quarto/fix-deno-path.patch b/pkgs/development/libraries/quarto/fix-deno-path.patch
deleted file mode 100644
index 895419712ad8..000000000000
--- a/pkgs/development/libraries/quarto/fix-deno-path.patch
+++ /dev/null
@@ -1,8 +0,0 @@
---- a/bin/quarto
-+++ b/bin/quarto
-@@ -125,4 +125,4 @@ fi
- # Be sure to include any already defined QUARTO_DENO_OPTIONS
- QUARTO_DENO_OPTIONS="--unstable --no-config --cached-only --allow-read --allow-write --allow-run --allow-env --allow-net --allow-ffi ${QUARTO_DENO_OPTIONS}"
- 
--"${QUARTO_DENO}" ${QUARTO_ACTION} ${QUARTO_DENO_OPTIONS} ${QUARTO_DENO_EXTRA_OPTIONS} "${QUARTO_IMPORT_ARGMAP}" "${QUARTO_TARGET}" "$@"
-+deno ${QUARTO_ACTION} ${QUARTO_DENO_OPTIONS} ${QUARTO_DENO_EXTRA_OPTIONS} "${QUARTO_IMPORT_ARGMAP}" "${QUARTO_TARGET}" "$@"