diff --git a/pkgs/applications/emulators/wine/base.nix b/pkgs/applications/emulators/wine/base.nix
index 8b1b4966ddab..c49fe9f1de54 100644
--- a/pkgs/applications/emulators/wine/base.nix
+++ b/pkgs/applications/emulators/wine/base.nix
@@ -78,7 +78,7 @@ stdenv.mkDerivation ((lib.optionalAttrs (buildScript != null) {
   ++ lib.optional fontconfigSupport      pkgs.fontconfig
   ++ lib.optional alsaSupport            pkgs.alsa-lib
   ++ lib.optional pulseaudioSupport      pkgs.libpulseaudio
-  ++ lib.optional (xineramaSupport && !waylandSupport) pkgs.xorg.libXinerama
+  ++ lib.optional (xineramaSupport && x11Support) pkgs.xorg.libXinerama
   ++ lib.optional udevSupport            pkgs.udev
   ++ lib.optional vulkanSupport          (if stdenv.isDarwin then moltenvk else pkgs.vulkan-loader)
   ++ lib.optional sdlSupport             pkgs.SDL2
@@ -93,7 +93,7 @@ stdenv.mkDerivation ((lib.optionalAttrs (buildScript != null) {
      CoreServices Foundation ForceFeedback AppKit OpenGL IOKit DiskArbitration PCSC Security
      ApplicationServices AudioToolbox CoreAudio AudioUnit CoreMIDI OpenCL Cocoa Carbon
   ])
-  ++ lib.optionals (stdenv.isLinux && !waylandSupport) (with pkgs.xorg; [
+  ++ lib.optionals (x11Support) (with pkgs.xorg; [
      libX11 libXi libXcursor libXrandr libXrender libXxf86vm libXcomposite libXext
   ])
   ++ lib.optionals waylandSupport (with pkgs; [
diff --git a/pkgs/applications/emulators/wine/default.nix b/pkgs/applications/emulators/wine/default.nix
index d3b285f36d78..2dc9b2625bf4 100644
--- a/pkgs/applications/emulators/wine/default.nix
+++ b/pkgs/applications/emulators/wine/default.nix
@@ -37,6 +37,7 @@
   usbSupport ? false,
   mingwSupport ? wineRelease != "stable",
   waylandSupport ? wineRelease == "wayland",
+  x11Support ? stdenv.isLinux,
   embedInstallers ? false, # The Mono and Gecko MSI installers
   moltenvk ? darwin.moltenvk # Allow users to override MoltenVK easily
 }:
@@ -51,7 +52,7 @@ let wine-build = build: release:
             v4lSupport saneSupport gphoto2Support krb5Support fontconfigSupport
             alsaSupport pulseaudioSupport xineramaSupport gtkSupport openclSupport
             tlsSupport openglSupport gstreamerSupport udevSupport vulkanSupport
-            sdlSupport usbSupport mingwSupport waylandSupport embedInstallers;
+            sdlSupport usbSupport mingwSupport waylandSupport x11Support embedInstallers;
         };
         inherit moltenvk;
       });