diff --git a/pkgs/development/tools/pydb/default.nix b/pkgs/development/tools/pydb/default.nix
deleted file mode 100644
index 5380bb686085..000000000000
--- a/pkgs/development/tools/pydb/default.nix
+++ /dev/null
@@ -1,25 +0,0 @@
-{ lib, stdenv, fetchurl, python2, emacs }:
-
-stdenv.mkDerivation rec {
-  pname = "pydb";
-  version = "1.26";
-
-  src = fetchurl {
-    url =  "mirror://sourceforge/sourceforge/bashdb/${pname}-${version}.tar.bz2";
-    sha256 = "1wlkz1hd5d4gkzhkjkzcm650c1lchj28hj36jx96mklglm41h4q1";
-  };
-
-  buildInputs = [ python2 emacs /* emacs is optional */ ];
-
-  preConfigure = ''
-    p="$(toPythonPath $out)"
-    configureFlags="$configureFlags --with-python=${python2.interpreter} --with-site-packages=$p"
-  '';
-
-  meta = {
-    description = "Python debugger with GDB-like commands and Emacs bindings";
-    homepage = "http://bashdb.sourceforge.net/pydb/";
-    license = lib.licenses.gpl3;
-    platforms = lib.platforms.all;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 6a42ebc5b5be..f7b962323fc4 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -1044,6 +1044,7 @@ mapAliases ({
   pulseaudioLight = throw "'pulseaudioLight' has been renamed to/replaced by 'pulseaudio'"; # Converted to throw 2022-02-22
   pulseeffects = throw "Use pulseeffects-legacy if you use PulseAudio and easyeffects if you use PipeWire"; # Added 2021-02-13
   pulseeffects-pw = easyeffects; # Added 2021-07-07
+  pydb = throw "pydb has been removed: abandoned by upstream"; # Added 2022-04-22
   pyIRCt = throw "pyIRCt has been removed from nixpkgs as it is unmaintained and python2-only";
   pyMAILt = throw "pyMAILt has been removed from nixpkgs as it is unmaintained and python2-only";
   pybind11 = throw "pybind11 was removed because pythonPackages.pybind11 for the appropriate version of Python should be used"; # Added 2021-05-14
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index bb38b9774bfe..fb431d0ce9b8 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -9488,8 +9488,6 @@ with pkgs;
 
   pycflow2dot = with python3.pkgs; toPythonApplication pycflow2dot;
 
-  pydb = callPackage ../development/tools/pydb { };
-
   pydf = callPackage ../applications/misc/pydf { };
 
   pyinfra = with python3Packages; toPythonApplication pyinfra;