diff --git a/maintainers/maintainer-list.nix b/maintainers/maintainer-list.nix
index 0f7e448b549a..0ae571f5cfa9 100644
--- a/maintainers/maintainer-list.nix
+++ b/maintainers/maintainer-list.nix
@@ -10507,6 +10507,13 @@
     githubId = 4477729;
     name = "Sergey Mironov";
   };
+  smitop = {
+    name = "Smitty van Bodegom";
+    email = "me@smitop.com";
+    matrix = "@smitop:kde.org";
+    github = "Smittyvb";
+    githubId = 10530973;
+  };
   sna = {
     email = "abouzahra.9@wright.edu";
     github = "s-na";
diff --git a/pkgs/applications/networking/mailreaders/meli/default.nix b/pkgs/applications/networking/mailreaders/meli/default.nix
index 354ab024c6d0..d0575b60653b 100644
--- a/pkgs/applications/networking/mailreaders/meli/default.nix
+++ b/pkgs/applications/networking/mailreaders/meli/default.nix
@@ -15,15 +15,15 @@
 
 rustPlatform.buildRustPackage rec {
   pname = "meli";
-  version = "alpha-0.7.1";
+  version = "alpha-0.7.2";
 
   src = fetchgit {
     url = "https://git.meli.delivery/meli/meli.git";
     rev = version;
-    sha256 = "00iai2z5zydx9bw0ii0n6d7zwm5rrkj03b4ymic0ybwjahqzvyfq";
+    sha256 = "sha256-cbigEJhX6vL+gHa40cxplmPsDhsqujkzQxe0Dr6+SK0=";
   };
 
-  cargoSha256 = "1r54a51j91iv0ziasjygzw30vqqvqibcnwnkih5xv0ijbaly61n0";
+  cargoSha256 = "sha256-ZE653OtXyZ9454bKPApmuL2kVko/hGBWEAya1L1KIoc=";
 
   cargoBuildFlags = lib.optional withNotmuch "--features=notmuch";
 
diff --git a/pkgs/development/compilers/tinycc/default.nix b/pkgs/development/compilers/tinycc/default.nix
index bb08b113ad50..b46dee899a33 100644
--- a/pkgs/development/compilers/tinycc/default.nix
+++ b/pkgs/development/compilers/tinycc/default.nix
@@ -19,12 +19,15 @@ stdenv.mkDerivation rec {
   '';
 
   configureFlags = [
-    "--cc=cc"
+    "--cc=$CC"
+    "--ar=$AR"
     "--crtprefix=${lib.getLib stdenv.cc.libc}/lib"
     "--sysincludepaths=${lib.getDev stdenv.cc.libc}/include:{B}/include"
     "--libpaths=${lib.getLib stdenv.cc.libc}/lib"
     # build cross compilers
     "--enable-cross"
+  ] ++ lib.optionals stdenv.hostPlatform.isMusl [
+    "--config-musl"
   ];
 
   preConfigure = ''
diff --git a/pkgs/development/libraries/libressl/CVE-2021-41581.patch b/pkgs/development/libraries/libressl/CVE-2021-41581.patch
new file mode 100644
index 000000000000..244792567192
--- /dev/null
+++ b/pkgs/development/libraries/libressl/CVE-2021-41581.patch
@@ -0,0 +1,53 @@
+Based on upstream https://github.com/openbsd/src/commit/62ceddea5b1d64a1a362bbb7071d9e15adcde6b1
+with paths switched to apply to libressl-portable and CVS header
+hunk removed.
+
+--- a/crypto/x509/x509_constraints.c
++++ b/crypto/x509/x509_constraints.c
+@@ -339,16 +339,16 @@
+ 			if (c == '.')
+ 				goto bad;
+ 		}
+-		if (wi > DOMAIN_PART_MAX_LEN)
+-			goto bad;
+ 		if (accept) {
++			if (wi >= DOMAIN_PART_MAX_LEN)
++				goto bad;
+ 			working[wi++] = c;
+ 			accept = 0;
+ 			continue;
+ 		}
+ 		if (candidate_local != NULL) {
+ 			/* We are looking for the domain part */
+-			if (wi > DOMAIN_PART_MAX_LEN)
++			if (wi >= DOMAIN_PART_MAX_LEN)
+ 				goto bad;
+ 			working[wi++] = c;
+ 			if (i == len - 1) {
+@@ -363,7 +363,7 @@
+ 			continue;
+ 		}
+ 		/* We are looking for the local part */
+-		if (wi > LOCAL_PART_MAX_LEN)
++		if (wi >= LOCAL_PART_MAX_LEN)
+ 			break;
+ 
+ 		if (quoted) {
+@@ -383,6 +383,8 @@
+ 			 */
+ 			if (c == 9)
+ 				goto bad;
++			if (wi >= LOCAL_PART_MAX_LEN)
++				goto bad;
+ 			working[wi++] = c;
+ 			continue; /* all's good inside our quoted string */
+ 		}
+@@ -412,6 +414,8 @@
+ 		}
+ 		if (!local_part_ok(c))
+ 			goto bad;
++		if (wi >= LOCAL_PART_MAX_LEN)
++			goto bad;
+ 		working[wi++] = c;
+ 	}
+ 	if (candidate_local == NULL || candidate_domain == NULL)
diff --git a/pkgs/development/libraries/libressl/default.nix b/pkgs/development/libraries/libressl/default.nix
index fb362ebbad2f..d70672f63ac3 100644
--- a/pkgs/development/libraries/libressl/default.nix
+++ b/pkgs/development/libraries/libressl/default.nix
@@ -1,8 +1,16 @@
-{ stdenv, fetchurl, lib, cmake, cacert, fetchpatch
+{ stdenv
+, fetchurl
+, lib
+, cmake
+, cacert
+, fetchpatch
 , buildShared ? !stdenv.hostPlatform.isStatic
 }:
 
 let
+  ldLibPathEnvName = if stdenv.isDarwin
+    then "DYLD_LIBRARY_PATH"
+    else "LD_LIBRARY_PATH";
 
   generic = { version, sha256, patches ? [] }: stdenv.mkDerivation rec {
     pname = "libressl";
@@ -42,6 +50,15 @@ let
       substituteInPlace ./tls/tls_config.c --replace '"/etc/ssl/cert.pem"' '"${cacert}/etc/ssl/certs/ca-bundle.crt"'
     '';
 
+    doCheck = true;
+    preCheck = ''
+      export PREVIOUS_${ldLibPathEnvName}=$${ldLibPathEnvName}
+      export ${ldLibPathEnvName}="$${ldLibPathEnvName}:$(realpath tls/):$(realpath ssl/):$(realpath crypto/)"
+    '';
+    postCheck = ''
+      export ${ldLibPathEnvName}=$PREVIOUS_${ldLibPathEnvName}
+    '';
+
     outputs = [ "bin" "dev" "out" "man" "nc" ];
 
     postFixup = ''
@@ -66,5 +83,15 @@ in {
   libressl_3_2 = generic {
     version = "3.2.5";
     sha256 = "1zkwrs3b19s1ybz4q9hrb7pqsbsi8vxcs44qanfy11fkc7ynb2kr";
+    patches = [
+      ./CVE-2021-41581.patch
+    ];
+  };
+  libressl_3_4 = generic {
+    version = "3.4.0";
+    sha256 = "1lhn76nd59p1dfd27b4636zj6wh3f5xsi8b3sxqnl820imsswbp5";
+    patches = [
+      ./CVE-2021-41581.patch
+    ];
   };
 }
diff --git a/pkgs/development/libraries/qcoro/default.nix b/pkgs/development/libraries/qcoro/default.nix
new file mode 100644
index 000000000000..62608e390f8b
--- /dev/null
+++ b/pkgs/development/libraries/qcoro/default.nix
@@ -0,0 +1,38 @@
+{ lib
+, mkDerivation
+, fetchFromGitHub
+, cmake
+, libpthreadstubs
+, qtbase
+}:
+
+mkDerivation rec {
+  pname = "qcoro";
+  version = "0.3.0";
+
+  src = fetchFromGitHub {
+    owner = "danvratil";
+    repo = "qcoro";
+    rev = "v${version}";
+    sha256 = "09543hpy590dndmlxmcm8c58m97blhaii4wbjr655qxdanhhxgzi";
+  };
+
+  outputs = [ "out" "dev" ];
+
+  nativeBuildInputs = [
+    cmake
+  ];
+
+  buildInputs = [
+    qtbase
+    libpthreadstubs
+  ];
+
+  meta = with lib; {
+    description = "Library for using C++20 coroutines in connection with certain asynchronous Qt actions";
+    homepage = "https://github.com/danvratil/qcoro";
+    license = licenses.mit;
+    maintainers = with maintainers; [ smitop ];
+    platforms = platforms.linux;
+  };
+}
diff --git a/pkgs/development/python-modules/libusb1/default.nix b/pkgs/development/python-modules/libusb1/default.nix
index 7d921a9c8976..f1b474b960f6 100644
--- a/pkgs/development/python-modules/libusb1/default.nix
+++ b/pkgs/development/python-modules/libusb1/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "libusb1";
-  version = "1.10.1";
+  version = "2.0.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8d70e5ef11a9facf304e696cc1d571c526bd9e02a8710a045b3b2567db7a54e0";
+    sha256 = "d3ba82ecf7ab6a48d21dac6697e26504670cc3522b8e5941bd28fb56cf3f6c46";
   };
 
   postPatch = ''
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 9b606baa75fb..9708264676ee 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -18686,11 +18686,12 @@ with pkgs;
   openvdb = callPackage ../development/libraries/openvdb {};
 
   inherit (callPackages ../development/libraries/libressl { })
-    libressl_3_2;
+    libressl_3_2
+    libressl_3_4;
 
   # Please keep this pointed to the latest version. See also
   # https://discourse.nixos.org/t/nixpkgs-policy-regarding-libraries-available-in-multiple-versions/7026/2
-  libressl = libressl_3_2;
+  libressl = libressl_3_4;
 
   boringssl = callPackage ../development/libraries/boringssl { };
 
@@ -32749,6 +32750,7 @@ with pkgs;
 
   wasm-pack = callPackage ../development/tools/wasm-pack {
     inherit (darwin.apple_sdk.frameworks) Security;
+    libressl = libressl_3_2;
   };
 
   wavegain = callPackage ../applications/audio/wavegain { };
diff --git a/pkgs/top-level/qt5-packages.nix b/pkgs/top-level/qt5-packages.nix
index a5adec5d78f6..21d11d339f3a 100644
--- a/pkgs/top-level/qt5-packages.nix
+++ b/pkgs/top-level/qt5-packages.nix
@@ -174,6 +174,8 @@ in (kdeFrameworks // plasmaMobileGear // plasma5 // plasma5.thirdParty // kdeGea
 
   qca-qt5 = callPackage ../development/libraries/qca-qt5 { };
 
+  qcoro = callPackage ../development/libraries/qcoro { };
+
   qcsxcad = callPackage ../development/libraries/science/electronics/qcsxcad { };
 
   qmltermwidget = callPackage ../development/libraries/qmltermwidget {