diff --git a/nixos/doc/manual/from_md/release-notes/rl-2211.section.xml b/nixos/doc/manual/from_md/release-notes/rl-2211.section.xml
index 864b6e47db26..be3adc4d3bed 100644
--- a/nixos/doc/manual/from_md/release-notes/rl-2211.section.xml
+++ b/nixos/doc/manual/from_md/release-notes/rl-2211.section.xml
@@ -267,6 +267,13 @@
           been removed due to lack of upstream maintenance.
         </para>
       </listitem>
+      <listitem>
+        <para>
+          The <literal>meta.mainProgram</literal> attribute of packages
+          in <literal>wineWowPackages</literal> now defaults to
+          <literal>&quot;wine64&quot;</literal>.
+        </para>
+      </listitem>
       <listitem>
         <para>
           (Neo)Vim can not be configured with
diff --git a/nixos/doc/manual/release-notes/rl-2211.section.md b/nixos/doc/manual/release-notes/rl-2211.section.md
index d4059e739322..3f9afe13f1d9 100644
--- a/nixos/doc/manual/release-notes/rl-2211.section.md
+++ b/nixos/doc/manual/release-notes/rl-2211.section.md
@@ -104,6 +104,8 @@ In addition to numerous new and upgraded packages, this release has the followin
   `python3.pkgs.influxgraph` packages, have been removed due to lack of upstream
   maintenance.
 
+- The `meta.mainProgram` attribute of packages in `wineWowPackages` now defaults to `"wine64"`.
+
 - (Neo)Vim can not be configured with `configure.pathogen` anymore to reduce maintainance burden.
 Use `configure.packages` instead.
 
diff --git a/pkgs/applications/emulators/wine/packages.nix b/pkgs/applications/emulators/wine/packages.nix
index 0af842ffc1b7..3b5aa19658ce 100644
--- a/pkgs/applications/emulators/wine/packages.nix
+++ b/pkgs/applications/emulators/wine/packages.nix
@@ -41,5 +41,6 @@ in with src; {
     monos =  [ mono ];
     buildScript = ./builder-wow.sh;
     platforms = [ "x86_64-linux" ];
+    mainProgram = "wine64";
   };
 }