diff --git a/pkgs/applications/virtualization/libgovirt/default.nix b/pkgs/applications/virtualization/libgovirt/default.nix
index 9c9da54c3632..0815781c21f7 100644
--- a/pkgs/applications/virtualization/libgovirt/default.nix
+++ b/pkgs/applications/virtualization/libgovirt/default.nix
@@ -20,6 +20,11 @@ stdenv.mkDerivation rec {
     sha256 = "HckYYikXa9+p8l/Y+oLAoFi2pgwcyAfHUH7IqTwPHfg=";
   };
 
+  patches = lib.optionals stdenv.isDarwin [
+    # The flag breaks the build on darwin and doesn't seem necessary
+    ./no-version-script-ld-flag.patch
+  ];
+
   nativeBuildInputs = [
     pkg-config
     gobject-introspection
@@ -46,8 +51,8 @@ stdenv.mkDerivation rec {
   meta = with lib; {
     homepage = "https://gitlab.gnome.org/GNOME/libgovirt";
     description = "GObject wrapper for the oVirt REST API";
-    maintainers = [ maintainers.amarshall ];
-    platforms = platforms.linux;
+    maintainers = with maintainers; [ amarshall atemu ];
+    platforms = with platforms; linux ++ darwin;
     license = licenses.lgpl21Plus;
   };
 }
diff --git a/pkgs/applications/virtualization/libgovirt/no-version-script-ld-flag.patch b/pkgs/applications/virtualization/libgovirt/no-version-script-ld-flag.patch
new file mode 100644
index 000000000000..a837c3bf0642
--- /dev/null
+++ b/pkgs/applications/virtualization/libgovirt/no-version-script-ld-flag.patch
@@ -0,0 +1,14 @@
+--- a/govirt/Makefile.in
++++ b/govirt/Makefile.in
+@@ -511,8 +511,7 @@
+ libgovirt_la_LDFLAGS = \
+ 	-version-info $(LT_CURRENT):$(LT_REVISION):$(LT_AGE)	\
+ 	-export-dynamic						\
+-	-no-undefined						\
+-	-Wl,--version-script=$(srcdir)/govirt.sym
++	-no-undefined
+ 
+ libgovirt_la_CFLAGS = \
+ 	$(WARNINGFLAGS_C)
+
+Diff finished.  Fri Oct 28 10:36:38 2022
diff --git a/pkgs/applications/virtualization/qemu/default.nix b/pkgs/applications/virtualization/qemu/default.nix
index 42a556a451fb..46bbc3b914b9 100644
--- a/pkgs/applications/virtualization/qemu/default.nix
+++ b/pkgs/applications/virtualization/qemu/default.nix
@@ -14,7 +14,7 @@
 , gtkSupport ? !stdenv.isDarwin && !xenSupport && !nixosTestRunner, gtk3, gettext, vte, wrapGAppsHook
 , vncSupport ? !nixosTestRunner, libjpeg, libpng
 , smartcardSupport ? !nixosTestRunner, libcacard
-, spiceSupport ? !stdenv.isDarwin && !nixosTestRunner, spice, spice-protocol
+, spiceSupport ? true && !nixosTestRunner, spice, spice-protocol
 , ncursesSupport ? !nixosTestRunner, ncurses
 , usbredirSupport ? spiceSupport, usbredir
 , xenSupport ? false, xen
diff --git a/pkgs/applications/virtualization/virt-viewer/default.nix b/pkgs/applications/virtualization/virt-viewer/default.nix
index ed882709aa14..2e8aa34286a6 100644
--- a/pkgs/applications/virtualization/virt-viewer/default.nix
+++ b/pkgs/applications/virtualization/virt-viewer/default.nix
@@ -29,7 +29,7 @@
 
 assert spiceSupport -> (
   gdbm != null
-  && libcap != null
+  && (stdenv.isLinux -> libcap != null)
   && spice-gtk_libsoup2 != null
   && spice-protocol != null
 );
@@ -76,12 +76,13 @@ stdenv.mkDerivation rec {
     libvirt-glib
     libxml2
     vte
-  ] ++ optionals spiceSupport [
+  ] ++ optionals spiceSupport ([
     gdbm
-    libcap
     spice-gtk_libsoup2
     spice-protocol
-  ];
+  ] ++ optionals stdenv.isLinux [
+    libcap
+  ]);
 
   # Required for USB redirection PolicyKit rules file
   propagatedUserEnvPkgs = optional spiceSupport spice-gtk_libsoup2;
@@ -94,8 +95,8 @@ stdenv.mkDerivation rec {
 
   meta = {
     description = "A viewer for remote virtual machines";
-    maintainers = [ maintainers.raskin ];
-    platforms = platforms.linux;
+    maintainers = with maintainers; [ raskin atemu ];
+    platforms = with platforms; linux ++ darwin;
     license = licenses.gpl2;
   };
   passthru = {
diff --git a/pkgs/development/libraries/spice/default.nix b/pkgs/development/libraries/spice/default.nix
index 4f639cf29f74..ed47a87ee116 100644
--- a/pkgs/development/libraries/spice/default.nix
+++ b/pkgs/development/libraries/spice/default.nix
@@ -22,6 +22,7 @@
 , libopus
 , gst_all_1
 , orc
+, gdk-pixbuf
 }:
 
 let
@@ -43,6 +44,9 @@ stdenv.mkDerivation rec {
     sha256 = "1xd0xffw0g5vvwbq4ksmm3jjfq45f9dw20xpmi82g1fj9f7wy85k";
   };
 
+  patches = [
+    ./remove-rt-on-darwin.patch
+  ];
   postPatch = ''
     install ${doxygen_sh} doxygen.sh
     patchShebangs build-aux
@@ -65,7 +69,6 @@ stdenv.mkDerivation rec {
   ];
 
   buildInputs = [
-    alsa-lib
     cyrus_sasl
     glib
     gst_all_1.gst-plugins-base
@@ -84,6 +87,10 @@ stdenv.mkDerivation rec {
     python3.pkgs.pyparsing
     spice-protocol
     zlib
+  ] ++ lib.optionals stdenv.isLinux [
+    alsa-lib
+  ] ++ lib.optionals stdenv.isDarwin [
+    gdk-pixbuf
   ];
 
   NIX_CFLAGS_COMPILE = "-fno-stack-protector";
@@ -108,7 +115,7 @@ stdenv.mkDerivation rec {
     homepage = "https://www.spice-space.org/";
     license = licenses.lgpl21;
 
-    maintainers = [ maintainers.bluescreen303 ];
-    platforms = platforms.linux;
+    maintainers = with maintainers; [ bluescreen303 atemu ];
+    platforms = with platforms; linux ++ darwin;
   };
 }
diff --git a/pkgs/development/libraries/spice/remove-rt-on-darwin.patch b/pkgs/development/libraries/spice/remove-rt-on-darwin.patch
new file mode 100644
index 000000000000..b3696d736af7
--- /dev/null
+++ b/pkgs/development/libraries/spice/remove-rt-on-darwin.patch
@@ -0,0 +1,18 @@
+--- a/meson.build
++++ b/meson.build
+@@ -103,11 +103,11 @@
+   spice_server_deps += dependency(dep)
+ endforeach
+ 
+-if host_machine.system() != 'windows'
++if (host_machine.system() != 'windows' and host_machine.system() != 'darwin')
+   foreach dep : ['rt', 'm']
+     spice_server_deps += compiler.find_library(dep)
+   endforeach
+-else
++elif host_machine.system() == 'windows'
+   foreach dep : ['ws2_32', 'shlwapi']
+     spice_server_deps += compiler.find_library(dep)
+   endforeach
+
+Diff finished.  Sun Oct 16 06:09:35 2022