diff --git a/pkgs/development/python-modules/tweedledum/default.nix b/pkgs/development/python-modules/tweedledum/default.nix
new file mode 100644
index 000000000000..4b24b3ff4efa
--- /dev/null
+++ b/pkgs/development/python-modules/tweedledum/default.nix
@@ -0,0 +1,37 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, cmake
+, ninja
+, scikit-build
+}:
+
+buildPythonPackage rec {
+  pname = "tweedledum";
+  version = "1.0.0";
+  format = "pyproject";
+
+  src = fetchFromGitHub{
+    owner = "boschmitt";
+    repo = "tweedledum";
+    rev = "v${version}";
+    hash = "sha256-59lJzdw9HLJ9ADxp/a3KW4v5aU/dYm27NSYoz9D49i4=";
+  };
+
+  nativeBuildInputs = [ cmake ninja scikit-build ];
+  dontUseCmakeConfigure = true;
+
+  pythonImportsCheck = [ "tweedledum" ];
+
+  # TODO: use pytest, but had issues with finding the correct directories
+  checkPhase = ''
+    python -m unittest discover -s ./python/test -t .
+  '';
+
+  meta = with lib; {
+    description = "A library for synthesizing and manipulating quantum circuits";
+    homepage = "https://github.com/boschmitt/tweedledum";
+    license = licenses.mit ;
+    maintainers = with maintainers; [ drewrisinger ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 0ebbe6b5210e..0c556e00afcd 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8565,6 +8565,8 @@ in {
 
   tvnamer = callPackage ../development/python-modules/tvnamer { };
 
+  tweedledum = callPackage ../development/python-modules/tweedledum { };
+
   tweepy = callPackage ../development/python-modules/tweepy { };
 
   twentemilieu = callPackage ../development/python-modules/twentemilieu { };