diff --git a/pkgs/development/compilers/spirv-llvm-translator/default.nix b/pkgs/development/compilers/spirv-llvm-translator/default.nix
index ace6c773770a..a268dafbdef0 100644
--- a/pkgs/development/compilers/spirv-llvm-translator/default.nix
+++ b/pkgs/development/compilers/spirv-llvm-translator/default.nix
@@ -3,31 +3,40 @@
 , cmake
 , pkg-config
 , lit
-, llvm_11
+, llvm
 , spirv-headers
 , spirv-tools
 }:
 
+let
+  llvmMajor = lib.versions.major llvm.version;
+
+  branch =
+    if llvmMajor == "11" then {
+      version = "unstable-2022-05-04";
+      rev = "99420daab98998a7e36858befac9c5ed109d4920"; # 265 commits ahead of v11.0.0
+      hash = "sha256-/vUyL6Wh8hykoGz1QmT1F7lfGDEmG4U3iqmqrJxizOg=";
+    } else throw "Incompatible LLVM version.";
+in
 stdenv.mkDerivation rec {
   pname = "SPIRV-LLVM-Translator";
-  version = "unstable-2022-05-04";
+  inherit (branch) version;
 
   src = fetchFromGitHub {
     owner = "KhronosGroup";
     repo = "SPIRV-LLVM-Translator";
-    rev = "99420daab98998a7e36858befac9c5ed109d4920";
-    sha256 = "sha256-/vUyL6Wh8hykoGz1QmT1F7lfGDEmG4U3iqmqrJxizOg=";
+    inherit (branch) rev hash;
   };
 
-  nativeBuildInputs = [ pkg-config cmake llvm_11.dev spirv-tools ];
+  nativeBuildInputs = [ pkg-config cmake llvm.dev spirv-tools ];
 
-  buildInputs = [ spirv-headers llvm_11 ];
+  buildInputs = [ spirv-headers llvm ];
 
   checkInputs = [ lit ];
 
   cmakeFlags = [
     "-DLLVM_INCLUDE_TESTS=ON"
-    "-DLLVM_DIR=${llvm_11.dev}"
+    "-DLLVM_DIR=${llvm.dev}"
     "-DBUILD_SHARED_LIBS=YES"
     "-DLLVM_SPIRV_BUILD_EXTERNAL=YES"
     # RPATH of binary /nix/store/.../bin/llvm-spirv contains a forbidden reference to /build/