diff --git a/pkgs/development/python-modules/unicorn/default.nix b/pkgs/development/python-modules/unicorn/default.nix
index 1f2876bdc693..8a568a47c0e4 100644
--- a/pkgs/development/python-modules/unicorn/default.nix
+++ b/pkgs/development/python-modules/unicorn/default.nix
@@ -20,7 +20,10 @@ buildPythonPackage rec {
   '';
 
   # needed on non-x86 linux
-  setupPyBuildFlags = lib.optionals stdenv.isLinux [ "--plat-name" "linux" ];
+  setupPyBuildFlags = lib.optionals stdenv.isLinux [ "--plat-name" "linux" ]
+                   # aarch64 only available from MacOS SDK 11 onwards, so fix the version tag.
+                   # otherwise, bdist_wheel may detect "macosx_10_6_arm64" which doesn't make sense.
+                   ++ lib.optionals (stdenv.isDarwin && stdenv.isAarch64) [ "--plat-name" "macosx_11_0" ];
 
   propagatedBuildInputs = [
     setuptools